Sky Sports will broadcast five games, including Monday Night Football, which will also air live on Channel 5.
The action kicks off on Thursday night as the Miami Dolphins host the Buffalo Bills at 1:15 a.m.
Neil Reynolds and the Sky Sports crew will be live in Minnesota at 6:00 p.m. on Sunday as the Vikings host the San Francisco 49ers.
The Cincinnati Bengals travel to face the Kansas City Chiefs at 9:25 p.m., followed by the Houston Texans hosting the Chicago Bears on Sunday Night Football at 1:20 a.m.
The final fixture of the weekend is Monday Night Football, where the Atlanta Falcons travel to face the Philadelphia Eagles at 1:15 a.m.
Thursday 12th September
Buffalo Bills @ Miami Dolphins
Sky Sports NFL, 1.15am
Amazon Prime, 8.15pm ET
Comms: Al Michaels, Kirk Herbstreit
Ref: Bill Vinovich
Sunday 15th September
San Francisco 49ers @ Minnesota Vikings
Sky Sports NFL, 6.00pm
CBS, 1.00pm ET
Comms: Kevin Harlan, Trent Green
Ref: Brad Allen
Cincinnati Bengals @ Kansas City Chiefs
Sky Sports NFL, 9.25pm
CBS, 4.25pm ET
Comms: Jim Nantz, Tony Romo
Ref: Alex Kemp
Chicago Bears @ Houston Texans
Sky Sports NFL, 1.20am
NBC, 8.20pm ET
Comms: Mike Tirico, Cris Collinsworth
Ref: Land Clark
Monday 16th September
Atlanta Falcons @ Philadelphia Eagles
Sky Sports NFL, 1.15am
Channel 5, 1.15am
ESPN, 8.15pm ET
Comms: Joe Buck, Troy Aikman
Ref: Craig Wrolstad
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